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Is Conduct Disorder Genetic?
- Heritability
- ~50%
- Inheritance
- polygenic
- Key genes
- MAOA DRD4
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Antisocial behaviour patterns in childhood with moderate heritability (~50%). Gene-environment interactions are significant.
How Genetic Is Conduct Disorder?
Conduct Disorder involves complex interactions between multiple genes and environmental factors. Heritability estimates range up to 50%, though no single gene determines outcome on its own.
Key genes associated with Conduct Disorder: MAOA DRD4. Variants in these genes have been identified through genome-wide association studies (GWAS) and clinical research as influencing susceptibility or severity.
Source: NIH
Does Family History Matter for Conduct Disorder?
Family history can be informative for Conduct Disorder, but its predictive power is limited because many genes — each with small effects — combine with environmental influences. A family history of the condition may prompt earlier or more frequent screening.
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