This page contains affiliate links. We may earn a commission if you purchase through them, at no extra cost to you.
Is Phaeochromocytoma Genetic?
- Heritability
- ~40%
- Inheritance
- autosomal-dominant
- Key genes
- VHL,RET,NF1,SDHB
CircleDNA's Premium Test includes personalised reports on Phaeochromocytoma risk. See your cancer genetic risk →
Phaeochromocytoma is an adrenal gland tumour. About 40% of cases have an identifiable hereditary cause making genetic testing important for all patients.
How Genetic Is Phaeochromocytoma?
Genetics plays a meaningful role in Phaeochromocytoma, with heritability estimated at around 40%. However, environmental factors — including diet, lifestyle, and exposure — also significantly influence risk.
Key genes associated with Phaeochromocytoma: VHL,RET,NF1,SDHB. Variants in these genes have been identified through genome-wide association studies (GWAS) and clinical research as influencing susceptibility or severity.
Source: MedlinePlus Genetics
Does Family History Matter for Phaeochromocytoma?
Family history does matter. Having close relatives with Phaeochromocytoma can increase your personal risk, though it is not deterministic. Maintaining a healthy lifestyle and regular screening remain important regardless of family background.
The world's most comprehensive at-home DNA test — 500+ reports covering diet, fitness, cancer risk, disease risk, and family planning.
Discover your genetic profile →