This page contains affiliate links. We may earn a commission if you purchase through them, at no extra cost to you.
Is Anorexia Nervosa Genetic?
- Heritability
- ~58%
- Inheritance
- polygenic
- Key genes
- ESR1 BDNF
CircleDNA's Premium Test covers 500+ health and ancestry reports. Explore your DNA →
Anorexia has heritability of ~58%. Genetic overlap with metabolic traits and OCD has been identified in recent GWAS.
How Genetic Is Anorexia Nervosa?
Anorexia Nervosa involves complex interactions between multiple genes and environmental factors. Heritability estimates range up to 58%, though no single gene determines outcome on its own.
Key genes associated with Anorexia Nervosa: ESR1 BDNF. Variants in these genes have been identified through genome-wide association studies (GWAS) and clinical research as influencing susceptibility or severity.
Source: NIH
Does Family History Matter for Anorexia Nervosa?
Family history can be informative for Anorexia Nervosa, but its predictive power is limited because many genes — each with small effects — combine with environmental influences. A family history of the condition may prompt earlier or more frequent screening.
The world's most comprehensive at-home DNA test — 500+ reports covering diet, fitness, cancer risk, disease risk, and family planning.
Discover your genetic profile →